{"id":844,"date":"2024-09-23T23:28:15","date_gmt":"2024-09-23T23:28:15","guid":{"rendered":"https:\/\/www.reflexmd.com\/blog\/?p=844"},"modified":"2025-04-21T23:30:16","modified_gmt":"2025-04-22T03:30:16","slug":"can-glp-1s-stop-binge-eating","status":"publish","type":"post","link":"https:\/\/www.reflexmd.com\/blog\/binge-eating\/can-glp-1s-stop-binge-eating\/","title":{"rendered":"Can a GLP-1 Stop Binge Eating?"},"content":{"rendered":"\n<p>We all can remember a time when we ate bowl after bowl of ice cream without planning to. Or felt so stuffed after three helpings of Thanksgiving sweet potato casserole that we wished we were wearing baggy sweatpants. For people with binge eating disorder (BED), however, out-of-control eating happens often\u2014at least once a week.<\/p>\n\n\n\n<p>BED can lead to major feelings of depression, guilt, and shame. It also increases risk for certain health conditions, such as obesity and type 2 diabetes. There are treatments that can help, however. And most recently, the medication GLP-1 has shown promise.\u00a0<\/p>\n\n\n\n<p>To learn more details about BED and the latest research about treatments, read on.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What is binge eating disorder?<\/h2>\n\n\n\n<p>BED is the most common eating disorder in America. It affects an estimated 2.3% of women and 0.3% of men, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7166070\/\">research<\/a> shows.&nbsp;Unlike <a href=\"https:\/\/www.nimh.nih.gov\/health\/topics\/eating-disorders\">bulimia,<\/a> in which people eat large amounts of food and then purge the food by vomiting or using laxatives (or in some cases, by over-exercising to avoid weight gain), BED involves overeating without the purging element.&nbsp;<\/p>\n\n\n\n<p>\u201cBinge eating disorder involves compulsive eating that is connected to the reward center in the brain,\u201d says Cathy Epps, PharmD, Chief Pharmacist with ReflexMD. \u201cIt has a different set of drivers than bulimia.\u201d Feelings of extreme shame often follow bouts of uncontrolled eating. This leads to restricted eating, which then can trigger another round of compulsive overeating, creating an endless cycle.<\/p>\n\n\n\n<p>This disorder can affect anyone at any age. However, BED most commonly occurs in teens and people in their 20s. The average age of onset is 21, according to the <a href=\"https:\/\/www.nimh.nih.gov\/health\/statistics\/eating-disorders\">National Institute of Mental Health<\/a>.<\/p>\n\n\n<div class=\"wp-block-reflex-interstitial-cta-block\"><style>.elementor-13 .elementor-element.elementor-element-a7d1126{--display:flex;--flex-direction:row;--container-widget-width:calc( ( 1 - var( --container-widget-flex-grow ) ) * 100% );--container-widget-height:100%;--container-widget-flex-grow:1;--container-widget-align-self:stretch;--flex-wrap-mobile:wrap;--align-items:center;--gap:24px 24px;--row-gap:24px;--column-gap:24px;--border-radius:4px 4px 4px 4px;--padding-top:0px;--padding-bottom:0px;--padding-left:0px;--padding-right:0px;}.elementor-13 .elementor-element.elementor-element-a7d1126:not(.elementor-motion-effects-element-type-background), .elementor-13 .elementor-element.elementor-element-a7d1126 > .elementor-motion-effects-container > .elementor-motion-effects-layer{background-color:var( 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.elementor-button{padding:12px 25px 12px 25px;}.elementor-13 .elementor-element.elementor-element-5c1e777 .elementor-button{font-size:var( --e-global-typography-7c01e8a-font-size );line-height:var( --e-global-typography-7c01e8a-line-height );letter-spacing:var( --e-global-typography-7c01e8a-letter-spacing );word-spacing:var( --e-global-typography-7c01e8a-word-spacing );}}\/* Start custom CSS for button, class: .elementor-element-3165b55 *\/.elementor-13 .elementor-element.elementor-element-3165b55 button {\n    white-space: nowrap;\n}\/* End custom CSS *\/\n\/* Start custom CSS for container, class: .elementor-element-c04910d *\/.elementor-13 .elementor-element.elementor-element-c04910d {\n    max-width: 900px;\n}\n.elementor-13 .elementor-element.elementor-element-c04910d p {\n    margin-bottom: 0;\n}\/* End custom CSS *\/\n\/* Start custom CSS for container, class: .elementor-element-a7d1126 *\/.elementor-13 .elementor-element.elementor-element-a7d1126 {\n    overflow: visible;\n}\/* End custom CSS *\/<\/style>\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"13\" class=\"elementor elementor-13 e-loop-item e-loop-item-937 post-937 cta type-cta status-publish hentry category-binge-eating\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-a7d1126 e-con-full e-flex e-con e-parent\" data-id=\"a7d1126\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-c04910d e-con-full e-flex e-con e-child\" data-id=\"c04910d\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9fb1137 elementor-widget elementor-widget-text-editor\" data-id=\"9fb1137\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tSilence the food noise once and for all!\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-46d501d elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"46d501d\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">If binge eating is a concern, a prescription GLP-1 can help.<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7047b33 elementor-widget elementor-widget-text-editor\" data-id=\"7047b33\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tTake 25% Off Any 3-month Plan using Code: SPRING25 at Checkout\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-59b9a6c e-con-full e-flex e-con e-child\" data-id=\"59b9a6c\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3165b55 elementor-align-left elementor-widget elementor-widget-button\" data-id=\"3165b55\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.reflexmd.com\/?question=gender\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-far-check-circle\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8C119.033 8 8 119.033 8 256s111.033 248 248 248 248-111.033 248-248S392.967 8 256 8zm0 48c110.532 0 200 89.451 200 200 0 110.532-89.451 200-200 200-110.532 0-200-89.451-200-200 0-110.532 89.451-200 200-200m140.204 130.267l-22.536-22.718c-4.667-4.705-12.265-4.736-16.97-.068L215.346 303.697l-59.792-60.277c-4.667-4.705-12.265-4.736-16.97-.069l-22.719 22.536c-4.705 4.667-4.736 12.265-.068 16.971l90.781 91.516c4.667 4.705 12.265 4.736 16.97.068l172.589-171.204c4.704-4.668 4.734-12.266.067-16.971z\"><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Start My Journey<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<\/div>\n\n\n<p>Symptoms of BED include eating an unusually large amount of food\u2014often thousands of calories, very quickly, even when you\u2019re not hungry\u2014until you are uncomfortably full. People with BED experience extreme distress about their behavior. They most commonly overeat when they are alone, according to the <a href=\"https:\/\/www.niddk.nih.gov\/health-information\/weight-management\/binge-eating-disorder\/definition-facts\">National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)<\/a>. Friends and family may have no idea they are dealing with this mental health condition.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">The connection between BED, obesity, and diabetes<\/h2>\n\n\n\n<p>People of any size can have BED, but it\u2019s more common in those who have obesity. And there\u2019s a strong correlation between BED and type 2 diabetes.&nbsp;<\/p>\n\n\n\n<p>One recent <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33554873\/\">study<\/a> found that around 20 percent of people with type 2 diabetes have an underlying eating disorder, most commonly BED. This may be because of the focus on food control and weight management needed to manage diabetes, according to NIDDK.&nbsp;<\/p>\n\n\n\n<p>There also may be a reverse connection at play. In those who have BED, excessive weight gain can contribute to a diabetes diagnosis.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Current treatments for BED<\/h2>\n\n\n\n<p>Getting compulsive overeating under control often takes a combination of medication and talk therapy. Cognitive behavioral therapy (CBT), <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16418545\/\">research<\/a> has found, is a recommended treatment. It involves recognizing the thoughts and triggers that lead to compulsive eating. It also means learning different ways to cope and to normalize eating.&nbsp;<\/p>\n\n\n\n<p>Doctors prescribe different <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s40263-024-01111-1\">medications<\/a> to treat BED, depending on the person\u2019s health and other conditions, such as depression, anxiety, or substance abuse. Some SSRI antidepressants can help, though they can come with a range of side effects. An anticonvulsant called topiramate (used to treat epilepsy) has been used off-label to treat the disorder. Right now, the only FDA-approved medication to treat BED is lisdexamfetamine.&nbsp;<\/p>\n\n\n\n<p>\u201cThis is a medication for ADHD that also acts as an appetite suppressant,\u201d Dr. Epps explains. It\u2019s been effective. But it\u2019s also a controlled substance with the potential to become addictive. And in recent years, there have been chronic shortages of the medication.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">The role of GLP-1 in BED treatment<\/h2>\n\n\n\n<p>There is a new game in town for treating BED. A few preliminary studies over the past few years have shown the potential of glucagon-like peptide (GLP-1) medications for treating BED, with minimal side effects. That said, much more research needs to be done.\u00a0<\/p>\n\n\n\n<p>Along with their effects on insulin and blood sugar, these medications work by both slowing digestion and sending signals to your brain about hunger and fullness. Side effects mainly include GI issues, such as constipation, diarrhea, and nausea.<\/p>\n\n\n\n<p>One retrospective <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2667368123000268\">study<\/a> of 98 patients attending an obesity clinic found that those taking GLP-1 had a significantly greater reduction in binge eating compared with those treated with lisdexamfetamine and topiramate.\u00a0<\/p>\n\n\n\n<p>Other GLP-1s may also help. A recent <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10915596\/\">review<\/a> found that GLP1-RAs such as liraglutide show promise in reducing how often people binge eat, their body weight, and comorbidities. This is possibly due to changes in how the brain signals the body that it\u2019s full as well as its food reward pathway.<\/p>\n\n\n\n<p>\u201cGLP-1 seems to have great potential for treatment of these disorders,\u201d says Dr. Epps. \u201cIt slows motility in the GI tract, and it gives that vagal response in which it goes up to your brain and tells you, <em>Hey, you\u2019re full, so stop eating!<\/em>\u201d&nbsp;<\/p>\n\n\n\n<p>Some of the research is showing that GLP-1 also suppresses the reward impulse in the brain in BED, she points out. It may also work on reducing compulsive behavior.&nbsp;<\/p>\n\n\n\n<p>Unlike lisdexamfetamine, GLP-1 is not a controlled substance. It also has other health benefits, primarily controlling blood sugar and aiding in weight loss, as well as potentially lowering the risk of heart and kidney disease, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10739421\/\">studies<\/a> show.&nbsp;<\/p>\n\n\n\n<p>More work needs to be done, adds Dr. Epps. \u201cThere aren&#8217;t any clear, double-blind, placebo-controlled studies right now, but there is definitely promising information coming out, and there is great potential for it,\u201d she says.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">The bottom line on BED and GLP-1<\/h2>\n\n\n\n<p>For people whose body weight and health conditions qualify them to take GLP-1 (generally that includes those with type 2 diabetes or a body weight in the overweight or obesity range, according to <a href=\"https:\/\/diet.mayoclinic.org\/us\/blog\/2024\/who-qualifies-for-semaglutide-injections\/\">Mayo Clinic<\/a>), the medication may also have the added benefit of getting binge eating disorder under control.<\/p>\n\n\n\n<p>It\u2019s important to remember that the drug works in conjunction with behavioral changes. \u201cHopefully, if someone has been on GLP-1 therapy and they\u2019re also receiving cognitive behavior therapy, by the end of the treatment, they will be in a different headspace and will have new coping behaviors they can use,\u201d Dr. Epps says.<strong>\u00a0 <\/strong>\u201cWhen it\u2019s used in conjunction with CBT, I think GLP-1 will really be able to help.\u201d\u00a0<\/p>\n\n\n\n<p>If you worry about binge eating and think GLP-1  might be right for you, talk to your doctor or <a href=\"https:\/\/chat2.reflexmd.com\/dchat\/\">chat<\/a> with a ReflexMD Wellness Advisor now.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Binge eating is the most common eating disorder in America, and it\u2019s often followed by feelings of depression, guilt, and shame. New research suggests the medication GLP-1 can slow or even stop the urge to binge\u2014and the shame that follows.<\/p>\n","protected":false},"author":8,"featured_media":980,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[75],"tags":[76,104],"class_list":["post-844","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-binge-eating","tag-food-noise","tag-glp-1"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>What Is Binge-Eating Disorder\u2014and How Can GLP-1s Help? | ReflexMD<\/title>\n<meta name=\"description\" content=\"Binge eating often leads to feelings of depression, guilt, and shame. 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